DDC purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DDC protein.
Immunogen
DDC (NP_000781.1, 1 a.a. ~ 480 a.a) full-length human protein.
Sequence
MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
DDC MaxPab rabbit polyclonal antibody. Western Blot analysis of DDC expression in NIH/3T3.Western Blot (Transfected lysate)
Western Blot analysis of DDC expression in transfected 293T cell line (H00001644-T04) by DDC MaxPab polyclonal antibody.
Lane 1: DDC transfected lysate(53.90 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — DDC
Entrez GeneID
1644GeneBank Accession#
NM_000790.2Protein Accession#
NP_000781.1Gene Name
DDC
Gene Alias
AADC
Gene Description
dopa decarboxylase (aromatic L-amino acid decarboxylase)
Gene Ontology
HyperlinkGene Summary
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
L-Dopa decarboxylase|aromatic L-amino acid decarboxylase
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Interactome
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Pathway
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Disease
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