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Last updated: 2016/10/23
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DDB2 monoclonal antibody (M01), clone 1F11

  • Catalog # : H00001643-M01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant DDB2.
  • Immunogen:
  • DDB2 (AAH00093, 1 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2b Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00001643-M01
    Western Blot detection against Immunogen (37.73 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Western Blot (Recombinant protein)
  • Gene Information
  • Entrez GeneID:
  • 1643
  • Gene Name:
  • DDB2
  • Gene Alias:
  • DDBB,FLJ34321,UV-DDB2
  • Gene Description:
  • damage-specific DNA binding protein 2, 48kDa
  • Gene Summary:
  • This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. [provided by RefSeq
  • Other Designations:
  • DDB p48 subunit,UV-damaged DNA-binding protein 2,damage-specific DNA binding protein 2,damage-specific DNA binding protein 2 (48kD),xeroderma pigmentosum group E protein
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