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Last updated: 2017/1/15

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DDB2 rabbit monoclonal antibody

  • Catalog # : H00001643-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human DDB2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human DDB2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human DDB2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1643
  • GeneBank Accession#:
  • DDB2
  • Gene Name:
  • DDB2
  • Gene Alias:
  • DDBB,FLJ34321,UV-DDB2
  • Gene Description:
  • damage-specific DNA binding protein 2, 48kDa
  • Gene Summary:
  • This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. [provided by RefSeq
  • Other Designations:
  • DDB p48 subunit,UV-damaged DNA-binding protein 2,damage-specific DNA binding protein 2,damage-specific DNA binding protein 2 (48kD),xeroderma pigmentosum group E protein
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