DCX DNAxPab

Catalog # H00001641-W01P

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Price

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Quantity

Size:200 ug
Price: USD $ 620.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Rabbit polyclonal antibody raised against a full-length human DCX DNA using DNAx™ Immune technology.DNAx Polyclonal Antibody,DNAx Polyclonal Antibodies,DNAx Pab,DNAx Polyclonal,DNA Immune,DNA Immunization,Immune Technology,Hard-to-Find Antibody,Hard-to-Find Antibodies,Hard-to-Find,Hard to Find,HardtoFind

    Technology

    DNAx™ Immune

    Immunogen

    Full-length human DNA

    Sequence

    MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM

    Host

    Rabbit

    Reactivity

    Human

    Purification

    Protein A

    Quality Control Testing

    Antibody reactive against mammalian transfected lysate.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Transfected lysate)

    Immunofluorescence (Transfected cell)

    Flow Cytometry (Transfected cell)

  • Gene Info — DCX

    Entrez GeneID

    1641

    GeneBank Accession#

    NM_178151.1

    Protein Accession#

    NP_835364.1

    Gene Name

    DCX

    Gene Alias

    DBCN, DC, LISX, SCLH, XLIS

    Gene Description

    doublecortin

    Omim ID

    300067 300121

    Gene Ontology

    Hyperlink

    Gene Summary

    In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    OTTHUMP00000062892|doublecortex|doublin|lissencephalin-X

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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