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Last updated: 2017/3/26

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DCX 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001641-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-DCX full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 40
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-DCX antibody (H00001641-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001641-T01
    DCX transfected lysate
    Western Blot
    QC Testing of H00001641-T01
    Lane 1: DCX transfected lysate ( 40 KDa).
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1641
  • Gene Name:
  • DCX
  • Gene Alias:
  • DBCN,DC,LISX,SCLH,XLIS
  • Gene Description:
  • doublecortin
  • Gene Summary:
  • In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000062892,doublecortex,doublin,lissencephalin-X
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