DCTD (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human DCTD partial ORF ( NP_001912.2, 69 a.a. - 178 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
RTAENKLDTKYPYVCHAELNAIMNKNSTDVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSINSRPSQKLQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DCTD
Entrez GeneID
1635GeneBank Accession#
NM_001921.2Protein Accession#
NP_001912.2Gene Name
DCTD
Gene Alias
MGC111062
Gene Description
dCMP deaminase
Omim ID
607638Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
deoxycytidylate deaminase
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Interactome
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Pathway
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Disease
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