DAO monoclonal antibody (M01), clone 2F5
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DAO.
Immunogen
DAO (NP_001908, 119 a.a. ~ 218 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DAO is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — DAO
Entrez GeneID
1610GeneBank Accession#
NM_001917Protein Accession#
NP_001908Gene Name
DAO
Gene Alias
DAAO, DAMOX, MGC35381, OXDA
Gene Description
D-amino-acid oxidase
Gene Ontology
HyperlinkGene Summary
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq
Other Designations
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