Immunoprecipitation of DGKA transfected lysate using anti-DGKA MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with DGKA purified MaxPab mouse polyclonal antibody (B01P) (H00001606-B01P).
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq