DAD1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DAD1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — DAD1
Entrez GeneID
1603GeneBank Accession#
NM_001344.1Protein Accession#
NP_001335.1Gene Name
DAD1
Gene Alias
OST2
Gene Description
defender against cell death 1
Omim ID
600243Gene Ontology
HyperlinkGene Summary
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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