DAB2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
DAB2 transfected lysate.
Western Blot
Lane 1: DAB2 transfected lysate ( 84.81 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-DAB2 full-length
Host
Human
Theoretical MW (kDa)
84.81
Interspecies Antigen Sequence
Mouse (83); Rat (83)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-DAB2 antibody (H00001601-B01) by Western Blots.
SDS-PAGE Gel
DAB2 transfected lysate.
Western Blot
Lane 1: DAB2 transfected lysate ( 84.81 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — DAB2
Entrez GeneID
1601GeneBank Accession#
BC003064.2Protein Accession#
AAH03064.1Gene Name
DAB2
Gene Alias
DOC-2, DOC2, FLJ26626
Gene Description
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
Omim ID
601236Gene Ontology
HyperlinkGene Summary
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta). [provided by RefSeq
Other Designations
disabled homolog 2|mitogen-responsive phosphoprotein
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Interactome
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Pathway
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Disease
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