DAB2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Tissue lysate)
DAB2 MaxPab polyclonal antibody. Western Blot analysis of DAB2 expression in human liver.
Western Blot (Cell lysate)
DAB2 MaxPab polyclonal antibody. Western Blot analysis of DAB2 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of DAB2 expression in transfected 293T cell line (H00001601-T01) by DAB2 MaxPab polyclonal antibody.
Lane 1: DAB2 transfected lysate(84.7 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DAB2 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DAB2 protein.
Immunogen
DAB2 (AAH03064.1, 1 a.a. ~ 770 a.a) full-length human protein.
Sequence
MSNEVETSATNGQPDQQAAPKAPSKKEKKKGPEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKKKIEEASKAVENGSEALMILDDQTNKLKSGVDQMDLFGDMSTPPDLNSPTESKDILLVDLNSEIDTNQNSLRENPFLTNGITSCSLPRPTPQASFLPENAFSANLNFFPTPNPDPFRDDPFTQPDQSTPSSFDSLKSPDQKKENSSSSSTPLSNGPLNGDVDYFGQQFDQISNRTGKQEAQAGPWPFSSSQTQPAVRTQNGVSEREQNGFSVKSSPNPFVGSPPKGLSIQNGVKQDLESSVQSSPHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFAPPVSEPSGQASPTGQPTALQPNPLDLFKTSAPAPVGPLVGLGGVTVTLPQAGPWNTASLVFNQSPSMAPGAMMGGQPSGFSQPVIFGTSPAVSGWNQPSPFAASTPPPVPVVWGPSASVAPNAWSTTSPLGNPFQSNIFPAPAVSTQPPSMHSSLLVTPPQPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQLRQPPAVPARKGEQTSSGTLSAFASYFNSKVGIPQENADHDDFDANQLLNKINEPPKPAPRQVSLPVTKSTDNAFENPFFKDSFGSSQASVASSQPVSSEMYRDPFGNPFA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (83)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
DAB2 MaxPab polyclonal antibody. Western Blot analysis of DAB2 expression in human liver.Western Blot (Cell lysate)
DAB2 MaxPab polyclonal antibody. Western Blot analysis of DAB2 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of DAB2 expression in transfected 293T cell line (H00001601-T01) by DAB2 MaxPab polyclonal antibody.
Lane 1: DAB2 transfected lysate(84.7 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DAB2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — DAB2
Entrez GeneID
1601GeneBank Accession#
BC003064.2Protein Accession#
AAH03064.1Gene Name
DAB2
Gene Alias
DOC-2, DOC2, FLJ26626
Gene Description
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
Omim ID
601236Gene Ontology
HyperlinkGene Summary
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta). [provided by RefSeq
Other Designations
disabled homolog 2|mitogen-responsive phosphoprotein
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Interactome
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Pathway
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Disease
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