DAB1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-DAB1 full-length
Host
Human
Theoretical MW (kDa)
60.94
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-DAB1 antibody (H00001600-B01) by Western Blots.
Western Blot
Lane 1: DAB1 transfected lysate ( 59.6 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
DAB1 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — DAB1
Entrez GeneID
1600GeneBank Accession#
BC067445Protein Accession#
AAH67445Gene Name
DAB1
Gene Alias
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Gene Description
disabled homolog 1 (Drosophila)
Omim ID
603448Gene Ontology
HyperlinkGene Summary
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000010045|OTTHUMP00000011753|disabled homolog 1
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Interactome
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Disease
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