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CYP11A1 Pre-design Chimera RNAi

  • Catalog # : H00001583-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), nuclear gene encoding mitochondrial protein, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000781
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 1583
  • Gene Name:
  • CYP11A1
  • Gene Alias:
  • CYP11A,P450SCC
  • Gene Description:
  • cytochrome P450, family 11, subfamily A, polypeptide 1
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq
  • Other Designations:
  • cholesterol 20-22 desmolase,cholesterol monooxygenase (side-chain cleaving),cytochrome P450, subfamily XIA,cytochrome P450, subfamily XIA (cholesterol side chain cleavage),cytochrome P450C11A1,steroid 20-22-lyase
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