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CYP3A4 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001576-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-CYP3A4 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 57.3
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-CYP3A4 antibody (H00001576-B01) by Western Blots.
    Western Blot
    QC Testing of H00001576-T01
    Lane 1: CYP3A4 transfected lysate ( 57.3 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00001576-T01
    CYP3A4 transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1576
  • Gene Name:
  • CYP3A4
  • Gene Alias:
  • CP33,CP34,CYP3A,CYP3A3,HLP,MGC126680,NF-25,P450C3,P450PCN1
  • Gene Description:
  • cytochrome P450, family 3, subfamily A, polypeptide 4
  • Gene Summary:
  • This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. [provided by RefSeq
  • Other Designations:
  • P450-III, steroid inducible,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4,cytochrome P450, subfamily IIIA, polypeptide 4,glucocorticoid-inducible P450,nifedipine o
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