CYP2C9 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CYP2C9 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKGG
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CYP2C9
Entrez GeneID
1559GeneBank Accession#
BC020754.1Protein Accession#
AAH20754.1Gene Name
CYP2C9
Gene Alias
CPC9, CYP2C, CYP2C10, MGC149605, MGC88320, P450IIC9
Gene Description
cytochrome P450, family 2, subfamily C, polypeptide 9
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq
Other Designations
OTTHUMP00000020135|cytochrome P-450 S-mephenytoin 4-hydroxylase|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 10|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9|cytochrome p4502C9|flavoprotein-linked mon
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Interactome
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Disease
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