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CYP2C9 rabbit monoclonal antibody

  • Catalog # : H00001559-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CYP2C9 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CYP2C9 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CYP2C9 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1559
  • Gene Name:
  • CYP2C9
  • Gene Alias:
  • CPC9,CYP2C,CYP2C10,MGC149605,MGC88320,P450IIC9
  • Gene Description:
  • cytochrome P450, family 2, subfamily C, polypeptide 9
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020135,cytochrome P-450 S-mephenytoin 4-hydroxylase,cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 10,cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9,cytochrome p4502C9,flavoprotein-linked mon
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