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CYP2C19 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00001557-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human CYP2C19 protein.
  • Immunogen:
  • CYP2C19 (AAI11847.1, 1 a.a. ~ 490 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 1557
  • Gene Name:
  • CYP2C19
  • Gene Alias:
  • CPCJ,CYP2C,P450C2C,P450IIC19
  • Gene Description:
  • cytochrome P450, family 2, subfamily C, polypeptide 19
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020132,OTTHUMP00000059588,S-mephenytoin 4-hydroxylase,cytochrome P-450 II C,cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19,flavoprotein-linked monooxygenase,mephenytoin 4'-hydroxylase,microsomal monooxygenase,xenobi
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