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CYP1A1 Pre-design Chimera RNAi

  • Catalog # : H00001543-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000499
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 1543
  • Gene Name:
  • CYP1A1
  • Gene Alias:
  • AHH,AHRR,CP11,CYP1,P1-450,P450-C,P450DX
  • Gene Description:
  • cytochrome P450, family 1, subfamily A, polypeptide 1
  • Gene Summary:
  • This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq
  • Other Designations:
  • aryl hydrocarbon hydroxylase,cytochrome P1-450, dioxin-inducible,cytochrome P450 1A1,cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1,flavoprotein-linked monooxygenase,xenobiotic monooxygenase
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