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Last updated: 2017/2/19

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CYBB Pre-design Chimera RNAi

  • Catalog # : H00001536-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000397
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 1536
  • Gene Name:
  • CYBB
  • Gene Alias:
  • CGD,GP91-1,GP91-PHOX,GP91PHOX,NOX2,p91-PHOX
  • Gene Description:
  • cytochrome b-245, beta polypeptide
  • Gene Summary:
  • Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031915,cytochrome b-245 beta polypeptide
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