CTSL2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CTSL2 full-length ORF ( NP_001324.2, 1 a.a. - 334 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
63.7
Interspecies Antigen Sequence
Mouse (75); Rat (76)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CTSL2
Entrez GeneID
1515GeneBank Accession#
NM_001333.2Protein Accession#
NP_001324.2Gene Name
CTSL2
Gene Alias
CATL2, CTSU, CTSV, MGC125957
Gene Description
cathepsin L2
Omim ID
603308Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. [provided by RefSeq
Other Designations
OTTHUMP00000021738|cathepsin L2, preproprotein|cathepsin U|cathepsin V
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Interactome
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Pathway
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Disease
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Publication Reference
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Exogenous cathepsin V protein protects human cardiomyocytes HCM from angiotensin Ⅱ-Induced hypertrophy.
Huang K, Gao L, Yang M, Wang J, Wang Z, Wang L, Wang G, Li H.
The International Journal of Biochemistry & Cell Biology 2017 May; 89:6.
Application:WB-Ti, Human, Human myocardial tissue.
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Exogenous cathepsin V protein protects human cardiomyocytes HCM from angiotensin Ⅱ-Induced hypertrophy.
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