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Last updated: 2016/12/4

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CTSK rabbit monoclonal antibody

  • Catalog # : H00001513-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CTSK peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CTSK is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CTSK peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1513
  • GeneBank Accession#:
  • CTSK
  • Gene Name:
  • CTSK
  • Gene Alias:
  • CTS02,CTSO,CTSO1,CTSO2,MGC23107,PKND,PYCD
  • Gene Description:
  • cathepsin K
  • Gene Summary:
  • The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032938,cathepsin O1,cathepsin O2,cathepsin X
  • Gene Pathway
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