Rabbit monoclonal antibody raised against a human CTSH peptide using ARM Technology.
Immunogen:
A synthetic peptide of human CTSH is used for rabbit immunization. Customer or Abnova will decide on the preferred peptide sequence.
Host:
Rabbit
Reactivity:
Human
Purification:
Protein A
Isotype:
IgG
Quality Control Testing:
Antibody reactive against human CTSH peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer:
In 1x PBS, pH 7.4
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note:
1. Customer may provide cell or tissue lysate for antibody screening. 2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Library Construction:
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression:
Overexpression vector and transfection into 293H cell line.
Deliverable:
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations:
N-benzoylarginine-beta-naphthylamide hydrolase,aleurain,cathepsin B3,cathepsin BA