CTPS monoclonal antibody (M01), clone 2G7-1D10
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant CTPS.
Immunogen
CTPS (AAH09408, 1 a.a. ~ 591 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGCRLSPRDTYSDRIGSSSPDSEITELKFPSINHD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (97)
Isotype
IgG2b kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (90.75 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CTPS
Entrez GeneID
1503GeneBank Accession#
BC009408Protein Accession#
AAH09408Gene Name
CTPS
Gene Alias
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Gene Description
CTP synthase
Omim ID
123860Gene Ontology
HyperlinkGene Summary
The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types [provided by RefSeq
Other Designations
OTTHUMP00000006322|OTTHUMP00000006323|cytidine 5'-triphosphate synthetase|cytidine 5-prime triphosphate synthetase
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Interactome
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Pathway
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Publication Reference
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PRENYLFLAVANONE COMPOUNDS AND USES THEREOF.
Huang, Chung-yang; Chen, Chia-nan; Huang, Wei-jan; Chi, Li- Ling; Chen, Pen-yuan; Lin, Chia-wei.
United States Patent Application 2010 Jun; US20100144857A1.
Application:WB-Ce, Human, MCF-7 cells.
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beta-Amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes.
David DC, Ittner LM, Gehrig P, Nergenau D, Shepherd C, Halliday G, Gotz J.
Proteomics 2006 Nov; 6(24):6566.
Application:IHC, WB, Human, Alzheimer’s disease patient brain samples.
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PRENYLFLAVANONE COMPOUNDS AND USES THEREOF.
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