CTNS (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CTNS partial ORF ( NP_004928, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MIRNWLTIFILFPLKLVEKCESSVSLTVPPVVKLENGSSTNVSLTLRPPLNATLVITFEITFRSKNITILELPDEVVVPPGVTNSSFQVTSQNVGQLTVY
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CTNS
Entrez GeneID
1497GeneBank Accession#
NM_004937Protein Accession#
NP_004928Gene Name
CTNS
Gene Alias
CTNS-LSB, PQLC4
Gene Description
cystinosis, nephropathic
Gene Ontology
HyperlinkGene Summary
This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
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Interactome
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