Immunoprecipitation of CTH transfected lysate using anti-CTH MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with CTH purified MaxPab mouse polyclonal antibody (B01P) (H00001491-B01P).
This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq