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Last updated: 2016/10/23
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CST3 monoclonal antibody, clone 1H4

  • Catalog # : H00001471-M04
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a full length native CST3.
  • Immunogen:
  • Native purified human CST3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2a, kappa
  • Quality Control Testing:
  • Antibody Reactive Against Native Protein

    QC Testing of H00001471-M04
    Western Blot detection against Immunogen (13 kDa)
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Western Blot (Recombinant protein)
  • Gene Information
  • Entrez GeneID:
  • 1471
  • Gene Name:
  • CST3
  • Gene Alias:
  • ARMD11,MGC117328
  • Gene Description:
  • cystatin C
  • Gene Summary:
  • The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000030440,OTTHUMP00000164181,OTTHUMP00000164182,bA218C14.4 (cystatin C),cystatin 3,cystatin C (amyloid angiopathy and cerebral hemorrhage),gamma-trace,neuroendocrine basic polypeptide,post-gamma-globulin
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