VCAN DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human VCAN DNA using DNAx™ Immune technology.
Technology
Immunogen
VCAN (AAH50524.1, 21 a.a. ~ 354 a.a) partial-length human DNA
Sequence
LHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of VCAN expression in transfected 293T cell line by VCAN DNAxPab polyclonal antibody.
Lane 1: VCAN transfected lysate(57.86 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — VCAN
Entrez GeneID
1462GeneBank Accession#
BC050524.1Protein Accession#
AAH50524.1Gene Name
VCAN
Gene Alias
CSPG2, DKFZp686K06110, ERVR, PG-M, WGN, WGN1
Gene Description
versican
Gene Ontology
HyperlinkGene Summary
This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Wagner syndrome (erosive vitreoretinopathy)|chondroitin sulfate proteoglycan 2 (versican)|versican proteoglycan
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Interactome
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Pathway
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Disease
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