CSF3R (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CSF3R partial ORF ( AAH53585, 25 a.a. - 134 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPHNLSCLMN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CSF3R
Entrez GeneID
1441GeneBank Accession#
BC053585Protein Accession#
AAH53585Gene Name
CSF3R
Gene Alias
CD114, GCSFR
Gene Description
colony stimulating factor 3 receptor (granulocyte)
Omim ID
138971Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq
Other Designations
CD114 antigen|OTTHUMP00000009703|OTTHUMP00000009704|OTTHUMP00000009705|colony stimulating factor 3 receptor|granulocyte colony stimulating factor receptor
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