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Last updated: 2016/12/4

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CSE1L rabbit monoclonal antibody

  • Catalog # : H00001434-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CSE1L peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CSE1L is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CSE1L peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1434
  • GeneBank Accession#:
  • CSE1L
  • Gene Name:
  • CSE1L
  • Gene Alias:
  • CAS,CSE1,MGC117283,MGC130036,MGC130037,XPO2
  • Gene Description:
  • CSE1 chromosome segregation 1-like (yeast)
  • Gene Summary:
  • Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq
  • Other Designations:
  • CSE1 chromosome segregation 1-like protein,OTTHUMP00000043373,cellular apoptosis susceptibility protein,chromosome segregation 1-like,importin-alpha re-exporter
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