Products

Immunoprecipitation-Western Blot

Entrez GeneID

Gene Name

CRYZ

Gene Alias

DKFZp779E0834, FLJ41475

Gene Description

crystallin, zeta (quinone reductase)

Omim ID

Gene Ontology

Gene Summary

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq

Other Designations

NADPH:quinone reductase|OTTHUMP00000011194|crystallin, zeta|quinone oxidoreductase