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CREBL2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001389-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-CREBL2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 13.31
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-CREBL2 antibody (H00001389-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001389-T01
    CREBL2 transfected lysate.
    Western Blot
    QC Testing of H00001389-T01
    Lane 1: CREBL2 transfected lysate ( 13.31 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1389
  • Protein Accession#:
  • -
  • Gene Name:
  • CREBL2
  • Gene Alias:
  • MGC117311,MGC138362
  • Gene Description:
  • cAMP responsive element binding protein-like 2
  • Gene Summary:
  • cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq
  • Other Designations:
  • -
  • Related Disease
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