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Last updated: 2016/10/23
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CREBL2 purified MaxPab rabbit polyclonal antibody (D01P)MaxPab

  • Catalog # : H00001389-D01P
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human CREBL2 protein.
  • Immunogen:
  • CREBL2 (NP_001301.1, 1 a.a. ~ 120 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of CREBL2 expression in transfected 293T cell line (H00001389-T02) by CREBL2 MaxPab polyclonal antibody.

    Lane 1: CREBL2 transfected lysate(13.80 KDa).
    Lane 2: Non-transfected lysate.
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  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
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  • Gene Information
  • Entrez GeneID:
  • 1389
  • Gene Name:
  • CREBL2
  • Gene Alias:
  • MGC117311,MGC138362
  • Gene Description:
  • cAMP responsive element binding protein-like 2
  • Gene Summary:
  • cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq
  • Other Designations:
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