CLDN3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CLDN3 full-length ORF ( AAH16056, 1 a.a. - 220 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
49.94
Interspecies Antigen Sequence
Mouse (91); Rat (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CLDN3
Entrez GeneID
1365GeneBank Accession#
BC016056Protein Accession#
AAH16056Gene Name
CLDN3
Gene Alias
C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
Gene Description
claudin 3
Omim ID
602910Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq
Other Designations
CPE-receptor 2|Clostridium perfringens enterotoxin receptor 2|OTTHUMP00000025042|OTTHUMP00000160506|claudin-3|ventral prostate.1-like protein
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Interactome
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Pathway
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