CPB2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CPB2 full-length
Host
Human
Theoretical MW (kDa)
48.4
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CPB2 antibody (H00001361-B01) by Western Blots.
SDS-PAGE Gel
CPB2 transfected lysate
Western Blot
Lane 1: CPB2 transfected lysate ( 48.4 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CPB2
Entrez GeneID
1361GeneBank Accession#
BC007057Protein Accession#
AAH07057Gene Name
CPB2
Gene Alias
CPU, PCPB, TAFI
Gene Description
carboxypeptidase B2 (plasma)
Omim ID
603101Gene Ontology
HyperlinkGene Summary
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000018364|OTTHUMP00000018365|bA139H14.2 (carboxypeptidase B2 (plasma))|carboxypeptidase B-like protein|carboxypeptidase B2 (plasma, carboxypeptidase U)|carboxypeptidase U|plasma carboxypeptidase B2|thrombin-activable fibrinolysis inhibitor|thromb
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Interactome
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Pathway
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Disease
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