CPB2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CPB2 full-length ORF ( NP_001863.2, 1 a.a. - 423 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
74.8
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CPB2
Entrez GeneID
1361GeneBank Accession#
NM_001872.3Protein Accession#
NP_001863.2Gene Name
CPB2
Gene Alias
CPU, PCPB, TAFI
Gene Description
carboxypeptidase B2 (plasma)
Omim ID
603101Gene Ontology
HyperlinkGene Summary
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000018364|OTTHUMP00000018365|bA139H14.2 (carboxypeptidase B2 (plasma))|carboxypeptidase B-like protein|carboxypeptidase B2 (plasma, carboxypeptidase U)|carboxypeptidase U|plasma carboxypeptidase B2|thrombin-activable fibrinolysis inhibitor|thromb
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Interactome
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Pathway
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Disease
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