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CPB2 rabbit monoclonal antibody

  • Catalog # : H00001361-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CPB2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CPB2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CPB2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1361
  • GeneBank Accession#:
  • CPB2
  • Gene Name:
  • CPB2
  • Gene Alias:
  • CPU,PCPB,TAFI
  • Gene Description:
  • carboxypeptidase B2 (plasma)
  • Gene Summary:
  • Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018364,OTTHUMP00000018365,bA139H14.2 (carboxypeptidase B2 (plasma)),carboxypeptidase B-like protein,carboxypeptidase B2 (plasma, carboxypeptidase U),carboxypeptidase U,plasma carboxypeptidase B2,thrombin-activable fibrinolysis inhibitor,thromb
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