CPB2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CPB2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CPB2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CPB2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CPB2
Entrez GeneID
1361GeneBank Accession#
CPB2Gene Name
CPB2
Gene Alias
CPU, PCPB, TAFI
Gene Description
carboxypeptidase B2 (plasma)
Omim ID
603101Gene Ontology
HyperlinkGene Summary
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000018364|OTTHUMP00000018365|bA139H14.2 (carboxypeptidase B2 (plasma))|carboxypeptidase B-like protein|carboxypeptidase B2 (plasma, carboxypeptidase U)|carboxypeptidase U|plasma carboxypeptidase B2|thrombin-activable fibrinolysis inhibitor|thromb
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