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COX10 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001352-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-COX10 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 48.84
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-COX10 antibody (H00001352-B02) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001352-T02
    COX10 transfected lysate.
    Western Blot
    QC Testing of H00001352-T02
    Lane 1: COX10 transfected lysate ( 48.84 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1352
  • Gene Name:
  • COX10
  • Gene Alias:
  • -
  • Gene Description:
  • COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
  • Gene Summary:
  • Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq
  • Other Designations:
  • cytochrome c oxidase assembly protein,cytochrome c oxidase subunit X,heme A: farnesyltransferase,heme A:farnesyltransferase
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