COX8A (Human) Recombinant Protein (P01)
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Specification
Product Description
Human COX8A full-length ORF ( NP_004065.1, 1 a.a. - 69 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSVLTPLLLRGLTGSARRLPVPRAKIHSLPPEGKLGIMELAVGLTSCFVTFLLPAGWILSHLETYRRPE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34
Interspecies Antigen Sequence
Mouse (68); Rat (67)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — COX8A
Entrez GeneID
1351GeneBank Accession#
NM_004074.2Protein Accession#
NP_004065.1Gene Name
COX8A
Gene Alias
COX, COX8, COX8-2, COX8L, VIII, VIII-L
Gene Description
cytochrome c oxidase subunit 8A (ubiquitous)
Omim ID
123870Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq
Other Designations
cytochrome c oxidase subunit 8A|cytochrome c oxidase subunit VIII
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