CORT DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CORT DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MYRHKNSWRLGLKYPPSSKEETQVPKTLISGLPGRKSSSRVGEKLQSAHKMPLSPGLLLLLLSGATATAALPLEGGPTGRDSEHMQEAAGIRKSSLLTFLAWWFEWTSQASAGPLIGEEAREVARRQEGAPPQQSARRDRMPCRNFFWKTFSSCK
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CORT
Entrez GeneID
1325GeneBank Accession#
NM_001302.3Protein Accession#
NP_001293.2Gene Name
CORT
Gene Alias
CST-14, CST-17, CST-29
Gene Description
cortistatin
Omim ID
602784Gene Ontology
HyperlinkGene Summary
The product of this gene is a neuropeptide with strong structural similarity to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. [provided by RefSeq
Other Designations
OTTHUMP00000001901|OTTHUMP00000044365|cortistatin-14|cortistatin-17|cortistatin-29|preprocortistatin
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Interactome
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Pathway
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Disease
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