CORT monoclonal antibody (M01), clone 8G10
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CORT is 0.03 ng/ml as a capture antibody.
Western Blot detection against Immunogen (43.6 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant CORT.
Immunogen
CORT (NP_001293.2, 1 a.a. ~ 155 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MYRHKNSWRLGLKYPPSSKEETQVPKTLISGLPGRKSSSRVGEKLQSAHKMPLSPGLLLLLLSGATATAALPLEGGPTGRDSEHMQEAAGIRKSSLLTFLAWWFEWTSQASAGPLIGEEAREVARRQEGAPPQQSARRDRMPCRNFFWKTFSSCK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (56); Rat (57)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (43.6 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CORT is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — CORT
Entrez GeneID
1325GeneBank Accession#
NM_001302.3Protein Accession#
NP_001293.2Gene Name
CORT
Gene Alias
CST-14, CST-17, CST-29
Gene Description
cortistatin
Omim ID
602784Gene Ontology
HyperlinkGene Summary
The product of this gene is a neuropeptide with strong structural similarity to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. [provided by RefSeq
Other Designations
OTTHUMP00000001901|OTTHUMP00000044365|cortistatin-14|cortistatin-17|cortistatin-29|preprocortistatin
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Interactome
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Pathway
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Disease
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