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COMT 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001312-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-COMT full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 24.4
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-COMT antibody (H00001312-B01) by Western Blots.
    Western Blot
    QC Testing of H00001312-T01
    Lane 1: COMT transfected lysate ( 24.4 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00001312-T01
    COMT transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1312
  • Gene Name:
  • COMT
  • Gene Alias:
  • -
  • Gene Description:
  • catechol-O-methyltransferase
  • Gene Summary:
  • Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq
  • Other Designations:
  • -
  • Related Disease
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