COMT (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human COMT.
Reactivity
Human
Quality Control Testing
Standard curve using recombinant protein ( H00001312-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 1 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-COMT (100 ug)
2. Detection antibody: mouse monoclonal anti-COMT, IgG2b Kappa (20 ug)
*Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — COMT
Entrez GeneID
1312Gene Name
COMT
Gene Alias
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Gene Description
catechol-O-methyltransferase
Gene Ontology
HyperlinkGene Summary
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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