COL6A2 monoclonal antibody (M01), clone 2C5-F2
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of COL6A2 expression in transfected 293T cell line by COL6A2 monoclonal antibody (M01), clone 2C5-F2.
Lane 1: COL6A2 transfected lysate(109 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (72.49 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant COL6A2.
Immunogen
COL6A2 (AAH02484, 1 a.a. ~ 425 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MTYVRETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFEAIQLDDEHIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSMRKQNVVPTVLALGSDVDMDVLTTLSLGDRAAVFHEKDYDSLAQPGFFDRFIRWIC
Host
Mouse
Reactivity
Human
Isotype
IgG2a kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (72.49 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of COL6A2 expression in transfected 293T cell line by COL6A2 monoclonal antibody (M01), clone 2C5-F2.
Lane 1: COL6A2 transfected lysate(109 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — COL6A2
Entrez GeneID
1292GeneBank Accession#
BC002484Protein Accession#
AAH02484Gene Name
COL6A2
Gene Alias
DKFZp586E1322, FLJ46862, PP3610
Gene Description
collagen, type VI, alpha 2
Gene Ontology
HyperlinkGene Summary
This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000115569|alpha 2 type VI collagen|collagen VI, alpha-2 polypeptide|collagen alpha-2(VI) chain|human mRNA for collagen VI alpha-2 C-terminal globular domain
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Interactome
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Pathway
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Disease
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Publication Reference
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Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer's disease.
Hondius DC, Eigenhuis KN, Morrema THJ, van der Schors RC, van Nierop P, Bugiani M, Li KW, Hoozemans JJM, Smit AB, Rozemuller AJM.
Acta Neuropathologica Communications 2018 Jun; 6(1):46.
Application：IHC-Fr, IHC-P, WB-Ti, Human, Occipital lobe tissue lysates.
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Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer's disease.
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