COL4A6 (Human) Recombinant Protein (P02)
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Specification
Product Description
Human COL4A6 full-length ORF ( AAH05305, 23 a.a. - 73 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GEKSYGKPCGGQDCSGSCQCFPEKGARHNLQLLNDMAGRLYHFSEVLPNLF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
31.35
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — COL4A6
Entrez GeneID
1288GeneBank Accession#
BC005305Protein Accession#
AAH05305Gene Name
COL4A6
Gene Alias
MGC88184
Gene Description
collagen, type IV, alpha 6
Gene Ontology
HyperlinkGene Summary
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023834|OTTHUMP00000023835|collagen IV, alpha-6 polypeptide|collagen alpha 6 type IV|collagen of basement membrane, alpha-6|dJ889N15.4 (Collagen Alpha 6(IV))|type IV alpha 6 collagen
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Interactome
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Pathway
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Disease
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