COL4A6 monoclonal antibody (M01), clone 1G11
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant COL4A6.
Immunogen
COL4A6 (AAH05305, 1 a.a. ~ 73 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MLINKLWLLLVTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARHNLQLLNDMAGRLYHFSEVLPNLF
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged COL4A6 is approximately 1ng/ml as a capture antibody.ELISA
In situ Proximity Ligation Assay (Cell)
Proximity Ligation Analysis of protein-protein interactions between OSM and COL4A6. HeLa cells were stained with anti-OSM rabbit purified polyclonal 1:1200 and anti-COL4A6 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue). -
Gene Info — COL4A6
Entrez GeneID
1288GeneBank Accession#
BC005305Protein Accession#
AAH05305Gene Name
COL4A6
Gene Alias
MGC88184
Gene Description
collagen, type IV, alpha 6
Gene Ontology
HyperlinkGene Summary
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023834|OTTHUMP00000023835|collagen IV, alpha-6 polypeptide|collagen alpha 6 type IV|collagen of basement membrane, alpha-6|dJ889N15.4 (Collagen Alpha 6(IV))|type IV alpha 6 collagen
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Interactome
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Disease
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