COL4A5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human COL4A5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human COL4A5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human COL4A5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — COL4A5
Entrez GeneID
1287GeneBank Accession#
COL4A5Gene Name
COL4A5
Gene Alias
ASLN, ATS, CA54, MGC167109, MGC42377
Gene Description
collagen, type IV, alpha 5
Gene Ontology
HyperlinkGene Summary
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Three transcript variants have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023838|collagen IV, alpha-5 polypeptide|collagen of basement membrane, alpha-5 chain|dA149D17.3|dA24A23.1|type IV collagen alpha 5
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Interactome
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Disease
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