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Last updated: 2017/4/30

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CCR8 rabbit monoclonal antibody

  • Catalog # : H00001237-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CCR8 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CCR8 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CCR8 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1237
  • GeneBank Accession#:
  • CCR8
  • Gene Name:
  • CCR8
  • Gene Alias:
  • CDw198,CKR-L1,CKRL1,CMKBR8,CMKBRL2,CY6,GPR-CY6,MGC129966,MGC129973,TER1
  • Gene Description:
  • chemokine (C-C motif) receptor 8
  • Gene Summary:
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq
  • Other Designations:
  • CC chemokine receptor 8,CC-chemokine receptor chemr1,chemokine (C-C) receptor 8,chemokine (C-C) receptor-like 2
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