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CCR7 rabbit monoclonal antibody

  • Catalog # : H00001236-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CCR7 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CCR7 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CCR7 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1236
  • GeneBank Accession#:
  • CCR7
  • Gene Name:
  • CCR7
  • Gene Alias:
  • BLR2,CD197,CDw197,CMKBR7,EBI1
  • Gene Description:
  • chemokine (C-C motif) receptor 7
  • Gene Summary:
  • The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq
  • Other Designations:
  • C-C chemokine receptor type 7,CC chemokine receptor 7,EBV-induced G protein-coupled receptor 1,Epstein-Barr virus induced G-protein coupled receptor,Epstein-Barr virus induced gene 1,MIP-3 beta receptor,chemokine (C-C) receptor 7,lymphocyte-specific G pro
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