CLCN1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human CLCN1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CLCN1
Entrez GeneID
1180GeneBank Accession#
BC111586Protein Accession#
AAI11587.1Gene Name
CLCN1
Gene Alias
CLC1, MGC138361, MGC142055
Gene Description
chloride channel 1, skeletal muscle
Gene Ontology
HyperlinkGene Summary
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). [provided by RefSeq
Other Designations
skeletal muscle chloride channel 1
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Interactome
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Disease
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