CLCA1 monoclonal antibody (M03), clone 2C10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CLCA1.
Immunogen
CLCA1 (NP_001276, 677 a.a. ~ 776 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ALGGVNAARRRVIPQQSGALYIPGWIENDEIQWNPPRPEINKDDVQHKQVCFSRTSSGGSFVASDVPNAPIPDLFPPGQITDLKAEIHGGSLINLTWTAP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (66); Rat (69)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CLCA1 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — CLCA1
Entrez GeneID
1179GeneBank Accession#
NM_001285Protein Accession#
NP_001276Gene Name
CLCA1
Gene Alias
CACC, CACC1, CLCRG1, FLJ95147, GOB5
Gene Description
chloride channel regulator 1
Omim ID
603906Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq
Other Designations
CLCA family member 1, chloride channel regulator|OTTHUMP00000011907|calcium-activated chloride channel protein 1|calcium-dependent chloride channel-1|chloride channel, calcium activated, family member 1
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Interactome
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Pathway
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Disease
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